I notice the problem with opening containers and such... the lag with RGW has definitely increased and I get a lot more stutters and hitches which can cause me to lose aim on a zombie or to fall off the edge of something I'm perched on randomly.
I am guessing it has to do with the massive size of the map being generated vs. zombie spawns at any given time. They've definitely got a lot of optimizing to do with this new RGW system. Alpha!